Guinness seeks medical records after Pakistani surgeons perform 10 liver transplants in under 24 hours

Surgeons at the Pakistan Kidney and Liver Institute and Research Centre (PKLI&RC) have achieved a remarkable feat, performing 10 liver transplant surgeries in an astonishing 23 hours and 20 minutes. This accomplishment has led Guinness World Records to request the institute's medical records, signaling a potential new world record.

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We have achieved a landmark breakthrough in transplantation medicine, demonstrating a novel clinical approach that expands organ utilisation and advances the treatment of rare metabolic diseases.

Dr. Prof. Faisal Saud Dar, dean of PKLI&RC, described the achievement as a "landmark breakthrough in transplantation medicine." He highlighted the use of a novel clinical approach that maximizes organ utilization and advances the treatment of rare metabolic diseases. The specialized team, comprising transplant surgeons, hepatologists, pediatricians, anesthesiologists, intensivists, nurses, and transplant coordinators, demonstrated exceptional surgical innovation and clinical excellence.

Among the 10 transplants were seven domino liver transplants and eight Auxiliary Partial Orthotopic Liver Transplants (APOLT). A domino transplant involves sequentially transplanting a donor's healthy liver into a second recipient, while APOLT is a complex procedure where a partial donor liver is implanted alongside the patient's existing liver. This innovative strategy allowed nine children and one adult to receive life-saving transplants from just three donors.

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This innovative transplant strategy enabled nine children and one adult to receive life-saving liver transplants from only three donors, demonstrating how advanced surgical expertise can substantially expand the impact of scarce donor organs.

Dr. Dar emphasized that this approach significantly expands the impact of scarce donor organs. All 10 patients have since been discharged and reunited with their families. The initiative successfully integrated two sophisticated transplant techniques, Domino Liver Transplantation and APOLT, into a highly coordinated clinical program, representing a significant advancement in treating rare genetic and metabolic diseases and offering new hope to patients with previously limited options.

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The scientific novelty of this initiative lies in the successful execution of a coordinated series of domino and auxiliary liver transplants for patients with rare inherited metabolic disorders.