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Kyung Hee University's College of Medicine Successfully Holds Special Lecture by Harvard Medical School Professor Taekjip Ha

From Hankyoreh · () Korean

Translated from Korean and summarized by DistantNews. Read the original for the full story.

At a glance

News Named sources Context piece
  • Professor Taekjip Ha from Harvard Medical School delivered a lecture at Kyung Hee University's College of Medicine.
  • The lecture focused on advancements in biomedical research through high-resolution technologies, specifically single-molecule biophysics.
  • Ha's research introduced techniques like single-molecule Förster resonance energy transfer (smFRET) and optical tweezers, with recent work addressing CRISPR-Cas9 off-target effects.

Kyung Hee University's College of Medicine was honored to host Professor Taekjip Ha, a world-renowned scholar in biophysics from Harvard Medical School. Professor Ha's lecture, titled 'Advancing Biomedical Research through High Resolution Technologies,' provided invaluable insights into the cutting edge of biomedical research, particularly focusing on the transformative potential of single-molecule biophysics.

When you enjoy the tension between the two extremes and the challenge at the boundary, you can open up a completely new paradigm.

· Professor Taekjip HaProfessor Ha encouraging the audience to embrace interdisciplinary challenges.

Professor Ha, a pioneer in observing and interpreting life phenomena at the single-molecule level, shared his vision for biophysics, moving beyond the traditional averaging of tens of thousands of molecules. He introduced groundbreaking techniques such as single-molecule Förster resonance energy transfer (smFRET) and optical tweezers. These methods allow for the direct observation of molecular movements and interactions, pushing the boundaries of scientific understanding.

Advancing Biomedical Research through High Resolution Technologies

· Professor Taekjip HaThe title of Professor Ha's lecture at Kyung Hee University.

The lecture garnered significant attention for its discussion of recent research that overcomes the 'off-target' side effects of CRISPR-Cas9 gene editing. Professor Ha's team has developed a method to control gene editing activity precisely, significantly reducing unintended cuts and achieving desired gene deletions in a high percentage of cells within an hour. This advancement holds immense promise for understanding cancer cell DNA repair mechanisms and developing novel treatments for intractable diseases. The university community, including faculty and students, benefited greatly from this enlightening session, which highlighted the power of interdisciplinary approaches in scientific innovation.

The team succeeded in inducing the desired gene deletion in more than 80% of cells within an hour by simultaneously cutting two target locations.

Describing the efficiency of Professor Ha's team's CRISPR-Cas9 research.
About this summary

Originally published by Hankyoreh in Korean. Translated, summarized, and contextualized automatically by DistantNews, with a note on how the source frames the story. Not individually reviewed before publishing. How this works.

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