Which COVID-19 variant is circulating in Guatemala?

Guatemala is observing an uptick in COVID-19 cases, with major hospitals like Roosevelt and General San Juan de Dios reporting nearly one hundred cases each and reinforcing preventive measures. Although official data has not yet fully reflected this trend, the increase is noticeable in healthcare facilities. The National Health Laboratory's latest genomic sequencing report indicates that the Omicron variant, with the XFG.14.1 lineage, is the predominant strain circulating in the country.

Globally, this Omicron lineage became dominant in January 2025, arising from a genetic combination of the LF.7 and LP.8.1.2 lineages. The World Health Organization (WHO) has classified it as a variant under surveillance, noting that current data does not suggest it causes more severe disease or higher mortality compared to other circulating variants. The last sequencing conducted in Guatemala was in December 2025, with new sample collection beginning to provide updated information.

Meanwhile, health authorities are also keeping an eye on the BA.3.2 variant, informally known as "Cicada." This sub-lineage of Omicron BA.3 has been under international observation by the WHO since December 5th and was present in approximately 23 countries by March 2026, according to the U.S. Centers for Disease Control and Prevention (CDC). Infectologists emphasize that there is currently no evidence indicating that BA.3.2 leads to more severe illness, with symptoms resembling a strong cold or flu: fever, sore throat, chills, and sometimes persistent headaches or nasal congestion.

Cases are generally mild to moderate, with patients recovering without hospitalization. While COVID-19 vaccines may reduce the risk of severe illness from BA.3.2, some studies suggest their effectiveness against symptomatic infection might be diminished. Experts advise consulting a doctor for any symptoms, especially for high-risk populations including those with comorbidities, individuals over 50, pregnant women, and young children. The article notes a challenge in Guatemala regarding vaccine availability.

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La variante se consolidó como la predominante a escala global y comenzó a documentarse en enero del 2025, según el panel de control de la Organización Mundial de la Salud (OMS) sobre el covid-19.