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๐Ÿ‡ฎ๐Ÿ‡ฉ Indonesia /Health & Science

Why Do People in Asia Often Experience Stomach Pain After Drinking Milk?

From Republika · () Indonesian

Translated from Indonesian, summarized and contextualized by DistantNews.

At a glance

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  • Around 68-70% of adults worldwide experience lactose intolerance, a condition where the body cannot digest lactose, the sugar found in milk.
  • In Asian countries like China, Japan, Korea, and Vietnam, lactose intolerance rates are exceptionally high, reaching 90-95%.
  • This prevalence is linked to a lack of a specific gene mutation ('lactase persistence') common in European populations, which allows for continued lactase enzyme production into adulthood.

Lactose intolerance affects a significant portion of the global adult population, with estimates suggesting 68-70% struggle to digest lactose, the natural sugar in milk and dairy products. This digestive disorder can lead to uncomfortable symptoms such as bloating, diarrhea, abdominal pain, and nausea after consuming dairy.

Lactose intolerance is more common among non-Caucasian races, including Asian communities. This is because they usually do not experience the mutation in the 'lactase persistence' gene that allows for the production of the lactase enzyme to continue into adulthood.

โ€” Prof. Ronny Rachman NoorAn ecological genetics expert explaining the genetic basis for higher lactose intolerance rates in Asian populations.

The prevalence of lactose intolerance varies significantly across different populations. While it affects roughly 5-15% of people of Caucasian descent, primarily due to a genetic mutation known as 'lactase persistence' that emerged in Northern Europe around 7,500 years ago, the situation is starkly different in Asia. In countries like China, Japan, Korea, and Vietnam, the rate of lactose intolerance soars to an astonishing 90-95%.

According to Prof. Ronny Rachman Noor, an ecological genetics expert at IPB University, this disparity is rooted in evolutionary genetics. Non-Caucasian populations, including those in Asia and Africa, generally lack the 'lactase persistence' gene mutation. This mutation enables the production of the lactase enzyme, which breaks down lactose, to continue throughout adulthood. In contrast, traditional diets in many Asian, African, and American regions did not historically center around fresh milk consumption, meaning the lactase persistence mutation was not strongly selected for in these populations.

The lactase persistence gene mutation that occurred about 7,500 years ago in Northern Europe allowed adults there to digest lactose well, so Caucasians tend to have low intolerance rates, only 5-15 percent.

โ€” Prof. Ronny Rachman NoorProfessor Ronny Rachman Noor detailing the historical development of lactase persistence in Europe.

Indonesia, situated in Southeast Asia, also experiences very high rates of lactose intolerance, ranging from 85% to 98%. The condition is present even in young children, with 21.3% of 3-5 year olds affected. This percentage increases dramatically with age, reaching 57.8% among 6-11 year olds, and continuing to rise through adolescence and into old age.

In Asia, Africa, and most of America, the culture of fresh milk consumption developed more slowly and was not a major part of the traditional diet. As a result, the lactase persistence mutation was not strongly selected and remains rare in these populations.

โ€” Prof. Ronny Rachman NoorProfessor Ronny Rachman Noor on the cultural and evolutionary factors influencing lactose tolerance.
DistantNews Editorial

Originally published by Republika in Indonesian. Translated, summarized, and contextualized by our editorial team with added local perspective. Read our editorial standards.